Single-subject research for nursing practice

Presenting the characteristics of single-subject research, the authors advocate greater use of the method by clinical nurse specialists and explore issues implicit in the research design (external validity, rigor, statistical versus clinical significance, ethics, and service versus research orientation). Replicated single-subject designs seem well suited to link process-based nursing practice and research. Such designs may make better investigative use of daily observations and interventions that are part of nursing practice. They propose that, despite concerns raised by others, single-subject research as a viable adjunct to existing research methods be considered as a means for increasing the contribution of clinical nurse specialists in the development of clinical nursing knowledge.