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[Severe imported malaria in adults: a retrospective study of 32 cases admitted to intensive care units]

P Corne1, K Klouche, D Basset

  • 1Service de réanimation médicale assistance respiratoire, hôpital Gui de Chauliac, 80, avenue Augustin-Fliche, 34295 Montpellier, France. p-corne@chu-montpellier.fr

Pathologie-Biologie
|December 15, 2004
PubMed
Abstract

Insights

Severe imported malaria, often acquired in sub-Saharan Africa, has a high mortality rate. Improving malaria chemoprophylaxis and earlier diagnosis are crucial for better patient outcomes.

Area of Science:

  • Tropical Medicine
  • Infectious Diseases
  • Critical Care Medicine

Context:

  • Severe imported malaria cases admitted to intensive care units (ICUs) are infrequently studied.
  • This retrospective study was conducted at the University Hospital of Montpellier.

Purpose:

  • To investigate the epidemiological features, admission criteria, treatment, and outcomes of severe imported malaria in ICU patients.
  • To identify factors contributing to mortality in this patient population.

Summary:

  • Thirty-two patients with severe falciparum malaria admitted to the ICU between 1997 and 2004 were analyzed.
  • Common admission criteria included impaired consciousness, acute renal failure, and high parasitemia.
  • The study found a 16% mortality rate, with causes including refractory shock, cerebral edema, and acute respiratory distress syndrome.

Impact:

  • Findings highlight the significant mortality associated with severe imported malaria, emphasizing the need for improved public health interventions.
  • The study underscores the importance of effective malaria chemoprophylaxis and prompt diagnosis to reduce mortality.
  • Results provide critical data for clinicians managing severe malaria cases in critical care settings.

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