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Updated: Aug 8, 2026

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Pseudomonas aeruginosa Induced Lung Injury Model
Published on: October 29, 2014
[Pneumonia induced by nocardia -- a case report]
H Frickmann1, S Jungblut, B Böddinghaus
1Medizinische Klinik, St. Elisabethen Krankenhaus, Katharina Kasper Kliniken, Frankfurt/Main.
Pneumologie (Stuttgart, Germany)
|December 15, 2004
Summary
This case study details a rare lung infection, nocardiosis, in an immunocompetent patient. Successful treatment involved targeted antibiotics, leading to full recovery without relapse.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Pulmonology
Background:
- Nocardiosis is a rare bacterial infection caused by Nocardia species.
- It often affects immunocompromised individuals but can occur in immunocompetent hosts.
- Pulmonary nocardiosis can present with diverse and nonspecific symptoms.
Observation:
- A 45-year-old patient presented with severe cough, discolored sputum, and dyspnea.
- Chest X-rays revealed inflammatory infiltration and shrinking of the right upper lung lobe.
- Microscopic examination of bronchial secretions showed Gram-positive, branching rods.
Findings:
- Nocardia transvalensis was identified using polymerase chain reaction (PCR).
- The patient was immunocompetent, making the presentation atypical.
- Antibiotic susceptibility testing guided therapy with Imipenem and Amikacin.
Implications:
- This case highlights the importance of considering nocardiosis in immunocompetent patients with unexplained pulmonary symptoms.
- Effective treatment relies on accurate identification and susceptibility-guided antibiotic selection.
- Prompt and appropriate management can lead to favorable outcomes and prevent relapse.
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