Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Changes in contrast sensitivity in glaucoma patients].

Anca-Doina Dimofte1, V Rusu, G Dimofte

  • 1Cabinet Oftalmologic Medoptica, Iaşi. DIMOFTE@MAIL.DNTIS.RO

Oftalmologia (Bucharest, Romania : 1990)
|December 16, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-precision measurement of the <i>W</i> boson mass with the CDF II detector.

Science (New York, N.Y.)·2022
Same author

Perioperative Immune Response Alternation. Can It Influence Cancer Recurrence?

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi·2018
Same author

Search for the Exotic Meson X(5568) with the Collider Detector at Fermilab.

Physical review letters·2018
Same author

Combined Forward-Backward Asymmetry Measurements in Top-Antitop Quark Production at the Tevatron.

Physical review letters·2018
Same author

Tevatron Combination of Single-Top-Quark Cross Sections and Determination of the Magnitude of the Cabibbo-Kobayashi-Maskawa Matrix Element V_{tb}.

Physical review letters·2015
Same author

Search for Resonances Decaying to Top and Bottom Quarks with the CDF Experiment.

Physical review letters·2015
Same journal

[Macular serpiginous choroiditis complicated by macular hole].

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

[Therapeutic approach in persistent diabetic macular edema].

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

[Preliminary results of treatment with aflibercept].

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

MANAGEMENT OF DIABETIC RETINOPATHY, PREVALENCE AND CLINICAL CLASSIFICATION.

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

[Changes in intraocular pressure depending on posture].

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

[Treatment for penetrating wound caused by metallic intraocular foreign body].

Oftalmologia (Bucharest, Romania : 1990)·2015
See all related articles

Glaucoma patients show significantly reduced temporal contrast sensitivity (TCS) across all tested frequencies. A flicker stimulus test demonstrates high validity for diagnosing glaucoma, making it a potential tool for screening and monitoring disease progression.

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Visual Science

Context:

  • Glaucoma is a progressive optic neuropathy characterized by visual field loss.
  • Early detection and monitoring of glaucoma are crucial for preserving vision.
  • Assessing visual function beyond standard visual acuity and perimetry is needed.

Purpose:

  • To evaluate changes in temporal contrast sensitivity (TCS) in patients diagnosed with glaucoma.
  • To assess the diagnostic utility of a novel flicker stimulus test for glaucoma detection.

Summary:

  • Temporal contrast sensitivity (TCS) was measured at 10, 20, and 30 Hz using a red flicker stimulus in 57 glaucoma patients.
  • A significant drop in the S score (a measure of TCS) was observed across all frequencies.
  • The S score positively correlated with mean deviation (MD) and negatively with the C/D ratio, indicating diffuse magnocellular system alterations.

Related Experiment Videos

Impact:

  • The flicker stimulus test, particularly at 30 Hz, showed high sensitivity and specificity (83.8% validity), suggesting its potential as a diagnostic tool for glaucoma.
  • The S score may serve as a valuable, low-cost, and rapid method for glaucoma screening and disease progression monitoring.