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Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Is one Gy equal to one Gy in chemo-radiotherapy or hormono-radiotherapy?
Renzo Corvò1, Laura Berretta, Valeria Andretta
1Istituto Nazionale per la Ricerca sul Cancro, Genova. corvo@hp380.ist.unige.it
Abstract:
The biological effect induced in the cell by a fixed dose of radiotherapy (e.g. 1 Gy) can be increased, reduced or significantly altered when chemotherapeutic or hormonal agents interact. A different timing of the combination between chemo/hormonotherapy and radiotherapy may also influence the cascade of effects induced by the dose of 1 Gy. Furthermore, patient, tumor and treatment-related factors are individual parameters which should be carefully considered for their potential impact on the radiation dose.
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