[Microalbuminuria and atherosclerosis risk factors in potentially healthy men--preliminary data]

The aim of the study was the assessment of occurrence of microalbuminuria (MI) and selected biochemical atherosclerosis risk factors in the group of potentially healthy men.

In the studied group were 200 men in mean age 28.7 +/- 8.1 years. In the first part of the study all participants filled environmental inquiry concerning the cardiovascular risk factors. On the basis of qualitatively and then quantitatively MI measurement the whole studied group was divided in two subgroups: A (18 men with MI) and B (182 men without MI). In the second part of the study, in both groups we investigated occurrence of abnormal levels of atherosclerosis risk factors such as: total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, uric acid, glucose, homocysteine (HCYS), C reactive protein (CRP). In the whole group we measured blood pressure, BMI and WHR.

In the group with MI we found mean HCYS levels 14.75 micromol/ml. This value was higher then in the group without MI (p < 0.0007). Mean level of CRP in group with MI was 0.24 mg/dl and was higher than in the group without MI (p < 0.04). Levels of HDL and ApoA in the group with MI were 49.05 mg/ml and 1.46 mg/ dl and were lower than in the group B (p < 0.03 and p < 0.036 respectively). The most important factors preceeding MI were age and level of LDL cholesterol.

Our preliminary data suggest that MI might be important atherosclerosis risk factor in potentially healthy men.