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Updated: Aug 17, 2026

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
Published on: May 10, 2016
[How to identify an occupational exposure to carcinogens and in which cases?]
Jean-Claude Pairon1, Jean-Charles Dalphin, Jacques Ameille
1Service de pneumologie et pathologie professionnelle, Centre hospitalier intercommunal de Créteil 94010. jcpairon@chicreteil.fr
Abstract:
Different tools may be used to evaluate previous occupational exposures, either in epidemiological studies or in clinical practice: occupational questionnaire followed by an expertise or the use of a job-exposure matrix; metrology; biometrology. In routine clinical practice, the main tool is an individual questionnaire to identify if a patient has worked in one of the main jobs or tasks known to be associated with an exposure to a definite carcinogen. As individual and collective consequences are important in case of recognition as an occupational disease, looking for the previous main occupational activities entailing exposure to carcinogens should be systematic in some sites of cancer: mesothelioma, lung, ethmoid, bladder and leukemia.
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