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Related Experiment Videos

Mohs surgery for malignant eccrine neoplasms.

John K Wildemore1, Jason B Lee, Tatyana R Humphreys

  • 1Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|December 21, 2004
PubMed
Summary
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Mohs micrographic surgery (MMS) shows promise for treating rare eccrine carcinomas (ECs), significantly reducing recurrence rates compared to traditional excision. Further research is needed to confirm its long-term efficacy.

Area of Science:

  • Dermatology
  • Surgical Oncology

Background:

  • Eccrine carcinomas (ECs) are rare, aggressive tumors with high recurrence rates after conventional surgery.
  • Mohs micrographic surgery (MMS) has limited reported use for EC, excluding microcystic adnexal carcinoma (MAC).

Observation:

  • This study reviews 7 cases of EC treated with MMS and analyzes 19 literature reports on MMS for non-MAC EC.
  • The objective was to compare MMS outcomes with conventional surgical excision for EC.

Findings:

  • No recurrences were reported in 19 cases of non-MAC EC treated with MMS over a 29-month follow-up.
  • Conventional surgical excision has a 10-70% local recurrence rate for these neoplasms.

Implications:

  • MMS may reduce recurrence rates for eccrine carcinomas compared to conventional surgery.

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  • Further studies and longer follow-up are required to establish MMS efficacy and optimal surgical margins for EC.