Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

RNAdb--a comprehensive mammalian noncoding RNA database.

Ken C Pang1, Stuart Stephen, Pär G Engström

  • 1ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia.

Nucleic Acids Research
|December 21, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gene body methylation suppresses intragenic transcription and permits epigenetic inheritance in a cnidarian.

Nature ecology & evolution·2026
Same author

Global changes in gene expression and splicing in alcoholic liver disease.

Scientific reports·2026
Same author

Correction: Widespread 3'UTR capped RNAs derive from G-rich regions in proximity to AGO2 binding sites.

BMC biology·2026
Same author

Multimodal imaging reveals a lysosomal drug reservoir that drives heterogeneous distribution of PARP inhibitors.

Nature communications·2026
Same author

Drug Development.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

JASPAR 2026: expansion of transcription factor binding profiles and integration of deep learning models.

Nucleic acids research·2025
Same journal

Correction to 'scSuperAnnotator: A platform for benchmarking comparison and visualizing automated cellular annotation methods for scRNA-seq data'.

Nucleic acids research·2026
Same journal

Correction to 'Differentiable partition function calculation for RNA'.

Nucleic acids research·2026
Same journal

Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and changing m6A modification in U1 and U6 snRNA.

Nucleic acids research·2026
Same journal

Bacillus subtilis DnaB forms multiple protein-protein interactions essential for DNA replication initiation.

Nucleic acids research·2026
Same journal

Multiple forms of protein-protein and DNA binding are exhibited by BrxC from the BREX phage restriction system.

Nucleic acids research·2026
Same journal

Biosynthesis of glycosylated 5-hydroxycytosine in the DNA of diverse viruses.

Nucleic acids research·2026
See all related articles

A new database, RNAdb, catalogs over 800 non-coding RNAs (ncRNAs) involved in development and disease. This resource supports the growing field of RNomics and understanding gene regulation.

Area of Science:

  • Genomics
  • Molecular Biology
  • Bioinformatics

Background:

  • Increasing identification of non-protein-coding transcripts with regulatory roles.
  • Many non-coding RNAs (ncRNAs) are developmentally regulated and linked to diseases.
  • Need for a centralized resource for studying ncRNAs.

Purpose of the Study:

  • To construct a comprehensive database (RNAdb) of mammalian non-coding RNAs.
  • To provide a searchable platform for experimentally studied and putative ncRNAs.
  • To support research in RNomics and mammalian gene regulation.

Main Methods:

  • Compilation of over 800 experimentally studied ncRNAs.
  • Inclusion of over 1100 putative antisense ncRNAs.
  • Integration of nearly 20,000 putative ncRNAs from human and murine cDNA libraries.

Related Experiment Videos

  • Exclusion of infrastructural RNAs (rRNAs, tRNAs).

    • Main Results:

    • RNAdb established with over 800 unique, experimentally validated ncRNAs.
    • Database includes microRNAs, snoRNAs, and large, spliced putative ncRNAs.
    • Contains over 1100 putative antisense ncRNAs and ~20,000 putative ncRNAs.
    • Provides a searchable resource at http://research.imb.uq.edu.au/RNAdb.

    Conclusions:

    • RNAdb serves as a foundational resource for RNomics.
    • Facilitates the characterization of ncRNA roles in mammalian gene expression.
    • Supports research into ncRNAs associated with development and disease.