Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Inhaled corticosteroid therapy does not control asthma.

Robert L Cowie1, Margot F Underwood, Stephen K Field

  • 1Calgary COPD and Asthma Program, University of Calgary, Calgary, Canada. cowie@ucalgary.ca

Canadian Respiratory Journal
|December 22, 2004
PubMed
Summary

Inhaled corticosteroid therapy for asthma control is less effective in real-world community settings than in clinical trials. Asthma control rates were significantly lower in patients using inhaled corticosteroids compared to those not using them.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Patient Factors and Clinical Efficacy of Early Identification and Treatment of Chronic Obstructive Pulmonary Disease and Asthma.

American journal of respiratory and critical care medicine·2025
Same author

Cough in Adults with Undiagnosed Respiratory Symptoms.

Annals of the American Thoracic Society·2025
Same author

Top 10 priorities for chronic cough: Canadian James Lind Alliance Priority-Setting Partnership (CAN-COUGH).

ERJ open research·2025
Same author

The McMaster Cough Severity Questionnaire (MCSQ): a cough severity instrument for patients with refractory chronic cough.

The European respiratory journal·2024
Same author

Association between lung function and sleep disorder symptoms in a community-based multi-site case-finding study.

Journal of sleep research·2024
Same author

Impact of Dyspnea on Adults With Respiratory Symptoms Without a Defined Diagnosis.

Chest·2024

Area of Science:

  • Pulmonology
  • Clinical Medicine
  • Pharmacotherapy

Background:

  • Randomized clinical trials (RCTs) confirm inhaled corticosteroid (ICS) efficacy for asthma control.
  • Real-world effectiveness data for ICS in community settings are limited.

Purpose of the Study:

  • To evaluate ICS effectiveness in controlling asthma outside of RCTs.
  • To assess asthma control rates associated with ICS use in the general population.

Main Methods:

  • Cross-sectional study analyzing community and university-based asthma patient populations.
  • Asthma control defined by Canadian Consensus Report criteria.
  • Association between self-reported ICS use (including dose) and asthma control assessed.

Main Results:

Related Experiment Videos

  • Overall asthma control achieved in 20% of 3427 subjects.
  • Only 15% of ICS users achieved asthma control versus 33% of non-users (P<0.000001).
  • Lower asthma control rates observed in ICS users in a real-world setting.

Conclusions:

  • ICS therapy effectiveness for asthma control may not translate from RCTs to community practice.
  • Real-world ICS use for asthma appears correlated with disease severity.
  • Further investigation into factors influencing ICS effectiveness in community settings is warranted.