Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Vasculitis associated with viral infections].

Pascal Cohen1, Loïc Guillevin

  • 1Service de médecine interne, Hôpital Avicenne, Bobigny (93).

Presse Medicale (Paris, France : 1983)
|December 24, 2004
PubMed
Summary

Viral infections like Hepatitis B and C can cause vasculitis, a condition affecting blood vessels. Prompt antiviral treatment offers a cure for some viral-induced vasculitis cases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of Rituximab for Induction and Maintenance Therapy in Patients 75 Years and Older With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

JAMA network open·2022
Same author

Use of biologics to treat relapsing and/or refractory polyarteritis nodosa: data from a European collaborative study.

Rheumatology (Oxford, England)·2022
Same author

Antiphospholipid syndrome: the burden of inadequate anticoagulation management.

Clinical and experimental rheumatology·2022
Same author

Remission and Low Disease Activity in Granulomatosis With Polyangiitis and Microscopic Polyangiitis: Prevalence and Impact on Damage Accrual.

Arthritis care & research·2022
Same author

Optimising ANCA-associated vasculitis management and infectious risks during the COVID-19 pandemic.

Clinical and experimental rheumatology·2022
Same author

Comparative study of granulomatosis with polyangiitis subsets according to ANCA status: data from the French Vasculitis Study Group Registry.

RMD open·2022

Area of Science:

  • Infectious Diseases
  • Immunology
  • Rheumatology

Context:

  • Systemic vasculitis is often idiopathic, but viral infections are identified causes in specific cases.
  • Viruses implicated include Hepatitis B (HBV), Hepatitis C (HCV), HIV, parvovirus B19, varicella-zoster, cytomegalovirus (CMV), and HTLV-1.
  • Each virus is associated with distinct vasculitic manifestations and target organs.

Purpose:

  • To elucidate the role of specific viral infections in the pathogenesis of various systemic vasculitides.
  • To highlight the distinct clinical presentations and affected systems associated with each viral trigger.
  • To underscore the potential for curative treatment with antiviral therapies in select viral vasculitis cases.

Summary:

  • Hepatitis B virus (HBV) causes 36-50% of polyarteritis nodosa cases with acute onset.
  • Hepatitis C virus (HCV) is linked to cryoglobulinemia with vasculitis, primarily affecting skin, nerves, and glomeruli.
  • Other viruses like HIV, parvovirus B19, varicella-zoster, CMV, and HTLV-1 are also associated with diverse vasculitic syndromes, including neurological and retinal involvement.
  • Vasculitis in immunocompromised patients is noted with CMV infection, affecting the digestive tract, CNS, and skin.
  • HTLV-1 infection can rarely lead to retinal vasculitis and neurological deficits.

Impact:

  • Identifies specific viral etiologies for vasculitis, enabling targeted diagnosis and treatment.
  • Demonstrates that antiviral therapy, sometimes combined with plasma exchange, can be curative for certain viral vasculitides.
  • Emphasizes the importance of considering viral infections in the differential diagnosis of vasculitis, especially when specific clinical patterns emerge.

Related Experiment Videos