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Published on: November 12, 2016
[Research on components of Cornus officinalis extracted by supercritical carbon dioxide]
Shu-yan Han1, Yang Pan, Guang-ming Yang
1Nanjing University of Traditional Chinese Medicine, Nanjing 210029, Jiangsu, China. shuyanhan@yahoo.com.cn
Objective:
To study the chemical constituents of Cornus officinalis extracted by supercritical carbon dioxide fluid extraction (SFE).
Method:
The process was performed at 40 centigrade with pressures of 15 MPa for 2 hours and with CO2 fluid and gas at the flow rate of 22.0 kg x h(-1) and 18.0 kg x h(-1) respectively. The chemical constituents of the SFE extractions were determined by GC-MS.
Result:
The total amount of extractable substances or yields by SFE is 2.42% (mass). 31 Chemical constituents were identified and their relative contents were determined by normalization method of area.
Conclusion:
The major components identified in the extractions are 1,2-benzenedicarboxylic acid, butyl 2-methylpropyl ester, isopropyl myristate etc.
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