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Updated: Aug 20, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
[Primary cardiac angiosarcoma: diagnostic utility of computed tomography and cardiac magnetic resonance]
Guillermo Romero-Farina1, Jaume Candell-Riera, Alvaro Beltrán-Ror
1Servicio de Cardiología, Hospital Universitari Vall d'Hebron, Barcelona, Spain. gromero@vhebron.net
Insights
Primary cardiac angiosarcomas are rare but aggressive tumors. Despite surgical intervention, these heart tumors often present late, leading to high mortality rates in patients.
Area of Science:
- Cardiology and Oncology
- Cardiac oncology
- Cardiovascular imaging
Background:
- Primary cardiac tumors are uncommon but present with diverse clinical symptoms.
- High mortality rates are associated with primary cardiac tumors due to late diagnosis and significant hemodynamic compromise.
Observation:
- This study presents three cases of cardiac angiosarcoma, a rare primary heart tumor.
- Two cases involved the right atrium, and one involved the left ventricle.
- Computed tomography-guided biopsy was used for diagnosis in one case.
Findings:
- Cardiac angiosarcomas often progress to large masses by the time symptoms appear.
- While Doppler echocardiography is used for initial diagnosis, advanced imaging like MRI and CT provide better anatomical detail.
- All three patients underwent surgical resection.
Implications:
- Despite surgical efforts, the short-term prognosis for patients with cardiac angiosarcoma remains poor, with a fatal outcome in all presented cases.
- Early diagnosis and advanced imaging are crucial for managing these aggressive heart tumors.
- Further research into novel therapeutic strategies is warranted for improving outcomes in cardiac angiosarcoma.
Abstract:
Primary cardiac tumors are infrequent, but their clinical presentation is variable and their associated mortality is high. By the time they produce symptoms and the diagnosis is made, they have usually progressed to a large mass causing considerable hemodynamic compromise. Although Doppler echocardiography is the usual technique for the initial diagnosis, magnetic resonance imaging or computed tomography can offer more anatomically useful information. We describe three patients with cardiac angiosarcoma, two in the right atrium and one in the left ventricle, the latter diagnosed by computed tomography-guided biopsy. All three patients underwent surgery, but the short-term course was fatal in all cases.
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