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Measuring Influenza Neutralizing Antibody Responses to A(H3N2) Viruses in Human Sera by Microneutralization Assays Using MDCK-SIAT1 Cells
Published on: November 22, 2017
Recent changes in influenza epidemiology and vaccination recommendations
1Department of Family Medicine and Clinical Epidemiology, University of Pittsburgh School of Medicine, 3518 Fifth Ave, Pittsburgh, PA 15261 USA. zimmer+@pitt.edu
Influenza causes thousands of deaths annually. To reduce childhood hospitalizations, inactivated influenza vaccines are recommended for children aged 6-23 months, while a live attenuated vaccine is available for healthy individuals aged 5-49 years.
Area of Science:
- Public Health
- Vaccinology
- Epidemiology
Background:
- Influenza remains a significant cause of mortality and morbidity in the United States.
- Pediatric influenza hospitalizations represent a substantial public health burden.
- Existing vaccination strategies aim to mitigate the impact of seasonal influenza.
Purpose of the Study:
- To summarize current recommendations for influenza vaccination in children.
- To highlight the availability and target populations for different types of influenza vaccines.
Main Methods:
- Review of current public health guidelines and vaccine licensure information.
- Analysis of epidemiological data on influenza-related hospitalizations in children.
Main Results:
- Inactivated influenza vaccine is routinely recommended for children aged 6-23 months.
- A live, attenuated influenza vaccine, licensed in 2003, is approved for healthy individuals aged 5-49 years.
Conclusions:
- Vaccination strategies are in place to protect vulnerable populations, including young children.
- Different influenza vaccine formulations cater to specific age groups and health statuses.
- Continued efforts in influenza prevention are crucial for public health.
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