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Physical activity in relation to cognitive decline in elderly men: the FINE Study
B M van Gelder1, M A R Tijhuis, S Kalmijn
1Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment, PO Box 1, Internal Postal Code 101, 3720 BA Bilthoven, The Netherlands. Boukje.van.Gelder@rivm.nl
Neurology
|December 30, 2004
Summary
Maintaining physical activity duration and intensity in old age is crucial for preserving cognitive function. A decrease in either can significantly accelerate cognitive decline over a decade.
Area of Science:
- Gerontology
- Neuroscience
- Public Health
Background:
- Physical activity is recognized for its potential benefits on cognitive health.
- Understanding the impact of changes in physical activity on cognitive decline in aging populations is essential.
Purpose of the Study:
- To examine the association between changes in physical activity duration and intensity and 10-year cognitive decline in elderly men.
- To identify specific thresholds of physical activity change that may influence cognitive trajectories.
Main Methods:
- Utilized data from 295 healthy male survivors (born 1900-1920) in the Finland, Italy, and the Netherlands Elderly (FINE) Study.
- Assessed physical activity using a validated questionnaire for retired men and cognitive function via the Mini-Mental State Examination from 1990 onward.
Main Results:
- A decrease in daily physical activity duration by over 60 minutes over 10 years led to a 1.7-point greater cognitive decline.
- Men in the lowest physical activity intensity quartile experienced 1.8 to 3.5 times stronger cognitive decline.
- Reduced physical activity intensity by at least half a standard deviation was linked to a 3.6 times greater cognitive decline compared to maintaining intensity.
Conclusions:
- Engaging in physical activities of at least medium-low intensity in later life may help delay cognitive decline.
- A reduction in the duration or intensity of physical activity accelerates cognitive decline more than maintaining previous levels.