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Peri-ictal SPECT and surgical treatment for intractable epilepsy related to schizencephaly
G D Cascino1, J R Buchhalter, J I Sirven
1Mayo Clinic, 200 First Street SW, Rochester, MN 55905. gcascino@mayo.edu.
Abstract:
The authors evaluated four patients with schizencephaly who underwent subtraction ictal SPECT coregistered to MRI (SISCOM) prior to epilepsy surgery. Three patients had a SISCOM alteration that was concordant with the epileptic brain tissue. Two of these patients were rendered seizure-free and one individual experienced a significant reduction in seizures. The patient with an indeterminate SISCOM had an unfavorable outcome. SISCOM is useful in evaluating patients with schizencephaly for epilepsy surgery.
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