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Chronic Intestinal Pseudo-Obstruction.

Kashyap V Panganamamula1, Henry P Parkman

  • 1Gastroenterology Section, Temple University School of Medicine, 8th Floor Parkinson Pavilion, 3401 N. Broad Street, Philadelphia, PA 19140, USA. henryp@temple.edu.

Current Treatment Options in Gastroenterology
|December 31, 2004
PubMed
Summary

Chronic intestinal pseudo-obstruction (CIP) is a rare motility disorder mimicking bowel obstruction. Management focuses on symptom control and nutritional support, often requiring dietary changes and medications.

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Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Motility Disorders

Background:

  • Chronic intestinal pseudo-obstruction (CIP) presents with symptoms of bowel obstruction without a physical blockage.
  • It is an uncommon condition with primary or secondary causes, impacting gastrointestinal motility.

Purpose of the Study:

  • To outline the diagnostic and management principles for chronic intestinal pseudo-obstruction.
  • To emphasize the importance of differentiating causes and assessing nutritional status.

Main Methods:

  • Clinical diagnosis and exclusion of mechanical obstruction.
  • Physiologic assessment using manometry and transit studies.
  • Nutritional status evaluation and therapeutic plan development.

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Main Results:

  • Management involves dietary modifications (small, low-fat, low-fiber meals), prokinetic agents (metoclopramide, erythromycin), and antibiotics for bacterial overgrowth.
  • Nutritional support, preferably enteral nutrition, is crucial.
  • Parenteral nutrition is reserved for refractory cases, with associated risks.

Conclusions:

  • Effective management of CIP requires a comprehensive approach including diagnosis, symptomatic treatment, and nutritional support.
  • Tailored therapeutic plans are essential for improving patient outcomes and preventing malnutrition.