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Published on: March 30, 2018
Epstein-Barr virus-associated hemophagocytic syndrome in a patient with lupus nephritis
Masato Isome1, Junzo Suzuki, Ai Takahashi
1Department of Pediatrics, Fukushima Medical University School of Medicine, 1-Hikarigaoka, 960-1295 Fukushima City, Fukushima, Japan. i-masato@fmu.ac.jp
Abstract:
Hemophagocytic syndrome (HPS) is an unusual but severe illness associated with a variety of infections, as well as genetic, malignant tumors, and autoimmune diseases. We report an 11-year-old girl with systemic lupus erythematosus and nephritis who developed HPS associated with Epstein-Barr virus reactivation. In our patient, the onset of reactive HPS might be related to immunosuppressive treatment during the course of lupus nephritis.
