Intellectual development of children born of mothers who fasted in Ramadan during pregnancy
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Fereidoun Azizi1, Hossein Sadeghipour, Behnam Siahkolah
1Endocrine Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, IR Iran. azizi@erc.ac.ir
Insights
Maternal Ramadan fasting during pregnancy did not negatively impact fetal brain development, as measured by children's intelligence quotient (IQ). This study found no significant differences in IQ scores between children whose mothers fasted and those whose mothers did not.
Area of Science:
- Obstetrics and Gynecology
- Developmental Psychology
- Public Health Nutrition
Background:
- The impact of Ramadan fasting during pregnancy on fetal neurodevelopment remains under-researched.
- Understanding potential long-term effects on cognitive outcomes is crucial for maternal and child health guidance.
Purpose of the Study:
- To investigate the association between maternal Ramadan fasting during pregnancy and the intelligence quotient (IQ) of their offspring.
- To determine if gestational fasting influences children's cognitive development.
Main Methods:
- A historical cohort study involving 191 children (4-13 years old).
- Compared 98 children whose mothers fasted during Ramadan pregnancy (cases) with 93 whose mothers did not (controls).
- Utilized Wechsler scales (WISC-R, WPPSI) to assess IQ, controlling for demographic and socioeconomic factors.
Main Results:
- No statistically significant differences in full-scale, performance, or verbal IQ scores were found between children of fasting and non-fasting mothers.
- Confounding variables like Caesarean section rates and breastfeeding duration differed, but did not negate the primary finding.
- Socioeconomic status explained approximately 17% of the variance in IQ scores.
Conclusions:
- Maternal fasting during Ramadan pregnancy does not appear to have an adverse effect on the intelligence quotient of the offspring.
- The findings suggest that Ramadan fasting, under the conditions studied, is not detrimental to fetal brain development concerning IQ.
Abstract:
The long-term effects of Ramadan fasting during pregnancy on the brain development of the fetus are still not clear. The aim of this study was to evaluate the effects of maternal fasting during Ramadan on the intelligence quotient of their progeny. A historical cohort study was conducted on 191 children aged between 4 to 13 years, 98 whose mothers fasted throughout Ramadan when they were pregnant with their children (case group) and 93 children whose mothers did not fast (control group). The children were selected from 15 schools via a questionnaire filled out by their mothers. Detailed demographic, medical history, and socioeconomic status data were collected by interviewing the mothers. All children aged between 6 to 13 were administered the Wechsler Intelligence Scale for Children-Revised (WISC-R), and those aged between 4 to 6 were administered Wechsler Preschool and Primary Scales of Intelligence (WPPSI), and intelligence quotient was estimated. Cases included 47 boys and 51 girls aged 8.5+/-2.5 years and controls included 44 boys and 49 girls aged 8.7+/-2.5 years. There were no significant differences in sex and age between two groups. Among background and confounder variables, the percentage of Caesarean section and the duration of breast-feeding were significantly different between case and control groups; 29% Caesarean section in cases vs. 45% in controls (p < 0.05) and 17.2+/-9 months breast-feeding for cases vs. 14.5+/-9 months for controls (p < 0.05). There were no significant differences in socioeconomic status of families between the groups whereas socioeconomic status accounted for approximately 17% of the variances in the average of full-scale intelligence quotient scores. Adjusted mean and standard deviation of full-scale intelligence quotient scores, performance and verbal, were 111+/-10, 109+/-11 and 110+/-11 for the case group and 112+/-10, 110+/-11 and 110+/-11 for the control group respectively. No significant differences were observed between the IQ scores of the two groups. Fasting during gestation did not adversely affect IQ of children whose mothers had fasted during Ramadan while being pregnant.
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