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High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
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Significance of the interferon (IFN) in the therapy

Sabina Mahmutović1, Edina Beslagić

  • 1Department of Microbiology, Faculty of Medicine, University of Sarajevo, Bosnia and Herzegovina.

Bosnian Journal of Basic Medical Sciences
|January 5, 2005
PubMed

Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Human IFN are divided on the sequence of amino-acids into three groups: Alpha, Beta and Gamma interferons. Recently are discovered new types of IFNs: Omega and Tau, but bigger than alpha molecules. Also, has been performed the division into two types: I and II. Besides the antiviral and antiproliferative effects, they have also the effect in the treatment of malignant diseases, and act protectively against the radiation.

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