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Related Experiment Video

Updated: Jan 19, 2026

Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods
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[Interventional therapy for complex congenital heart disease].

Ai-qing Zhou1, Rong-fa Wang, Wei Gao

  • 1Xinhua Hospital, Shanghai Children's Medical Center, Shanghai Second Medical University, Shanghai 200127, China.

Zhonghua Er Ke Za Zhi = Chinese Journal of Pediatrics
|January 6, 2005
PubMed
Summary

Interventional cardiac catheterization offers effective treatment for complex congenital heart diseases, improving outcomes. Combining surgical procedures with catheterization therapy yields better results for pediatric patients.

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Area of Science:

  • Pediatric Cardiology
  • Interventional Cardiology
  • Congenital Heart Disease

Context:

  • Advances in interventional cardiac catheterization have transformed treatment strategies for congenital heart diseases.
  • Complex congenital heart diseases require innovative therapeutic approaches.

Purpose:

  • To evaluate the efficacy of therapeutic cardiac catheterization in managing complex congenital heart diseases.
  • To assess the role of interventional catheterization in pediatric cardiac care.

Summary:

  • Balloon atrial septostomy (BAS) improved oxygen saturation in Transposition of Great Arteries (TGA).
  • Percutaneous balloon pulmonary valvuloplasty (PBPV) relieved pulmonary stenosis in Tetralogy of Fallot (TOF).
  • Transcatheter coil embolization successfully occluded collateral vessels and shunts, while device closure addressed fenestration post-Fontan procedure.

Impact:

  • Interventional catheterization provides a less invasive treatment option for various complex congenital heart conditions.
  • The combination of surgical procedures and interventional catheterization therapy is recommended for improved patient outcomes.
  • Successful interventions included improved SaO2 in TGA, relief of pulmonary stenosis in TOF, and effective vessel occlusion.