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Stent-assisted coil placement for unruptured cerebral aneurysms
Pascal Jabbour1, Christopher Koebbe, Erol Veznedaroglu
1Department of Neurosurgery, Thomas Jefferson University School of Medicine, Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania, USA. Pascal.jabbour@mail.tju.edu
Neurosurgical Focus
|January 7, 2005
Summary
The Neuroform microstent aids in treating wide-necked cerebral aneurysms with coil placement, achieving 75% successful occlusion in a study of 32 patients. Further data is needed for long-term outcomes.
Area of Science:
- Neurosurgery
- Endovascular Therapy
- Medical Devices
Background:
- Wide-necked cerebral aneurysms pose significant neurosurgical challenges.
- Stent development enables endovascular treatment while maintaining parent vessel patency.
- Long-term efficacy of stent-assisted coil placement for aneurysms requires investigation.
Purpose of the Study:
- To evaluate the use of the Neuroform microstent for treating unruptured wide-necked cerebral aneurysms.
- To assess the short-term occlusion rates and complications associated with this technique.
Main Methods:
- Thirty-two patients with unruptured wide-necked intracranial aneurysms underwent stent-assisted coil embolization.
- Patients received antiplatelet therapy pre-procedure and anticoagulation post-procedure.
- The Neuroform microstent was deployed across the aneurysm neck, followed by coil insertion.
Main Results:
- Successful occlusion of at least 90% was achieved in 24 patients (75%).
- Complete occlusion (0%) was observed in five patients (15%).
- Two thromboembolic events occurred (6.3% complication rate), one stent-related.
Conclusions:
- Intracranial stents, like the Neuroform microstent, are increasingly vital in endovascular treatment of wide-necked cerebral aneurysms.
- Technical refinements and long-term data are necessary to optimize outcomes.
- This approach offers a method to improve aneurysm occlusion while preserving parent vessel integrity.