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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
Published on: November 4, 2015
Pulmonary thromboembolism in children
Paul S Babyn1, Harpal K Gahunia, Patricia Massicotte
1Department of Pediatric Diagnostic Imaging, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, Canada, M5G 1X5. paul.babyn@sickkids.ca
Insights
Pediatric pulmonary thromboembolism (PTE) is rare and often found post-mortem. Early recognition of risk factors and varied presentations is crucial for timely diagnosis and treatment in children.
Area of Science:
- Pediatric Pulmonology
- Pediatric Critical Care Medicine
- Pediatric Hematology/Oncology
Background:
- Pulmonary thromboembolism (PTE) is infrequently diagnosed in pediatric patients, often discovered incidentally or during autopsy.
- The incidence of pediatric PTE is influenced by underlying conditions, diagnostic methods, and clinical suspicion.
- Numerous risk factors contribute to pediatric PTE, including central venous lines, trauma, surgery, malignancy, and dehydration.
Purpose of the Study:
- To review the risk factors, clinical presentation, and treatment of pulmonary embolism in children.
- To highlight current diagnostic tools and protocols for evaluating pediatric PTE.
- To emphasize the importance of recognizing various types of embolism in childhood.
Main Methods:
- Review of existing literature on pediatric pulmonary thromboembolism.
- Analysis of risk factors, clinical manifestations, and treatment strategies.
- Evaluation of diagnostic approaches and protocols for PTE in pediatric populations.
Main Results:
- Pediatric PTE incidence varies based on underlying disease, diagnostic techniques, and suspicion levels.
- A wide range of risk factors are associated with PTE in children.
- No single noninvasive test is sufficient; a combination of diagnostic procedures is necessary.
Conclusions:
- Accurate diagnosis of pediatric PTE requires a comprehensive approach, considering diverse risk factors and clinical signs.
- Effective management of PTE in children necessitates prompt identification and appropriate treatment strategies.
- Understanding different types of embolism in childhood is vital for appropriate therapeutic interventions.
Abstract:
Pulmonary thromboembolism (PTE) is uncommonly diagnosed in the pediatric patient, and indeed often only discovered on autopsy. The incidence of pediatric PTE depends upon the associated underlying disease, diagnostic tests used, and index of suspicion. Multiple risk factors can be found including: peripartum asphyxia, dyspnea, haemoptysis, chest pain, dehydration, septicemia, central venous lines (CVLs), trauma, surgery, ongoing hemolysis, vascular lesions, malignancy, renal disease, foreign bodies or, uncommonly, intracranial venous sinus thrombosis, burns, or nonbacterial thrombotic endocarditis. Other types of embolism can occur uncommonly in childhood and need to be recognized, as the required treatment will vary. These include pulmonary cytolytic thrombi, foreign bodies, tumor and septic emboli, and post-traumatic fat emboli. No single noninvasive test for pulmonary embolism is both sensitive and specific. A combination of diagnostic procedures must be used to identify suspect or confirmed cases of PTE. This article reviews the risk factors, clinical presentation and treatment of pulmonary embolism in children. It also highlights the current diagnostic tools and protocols used to evaluate pulmonary embolism in pediatric patients.
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