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Surgical treatment of infective endocarditis
Akram Saleh1, Keith Dawkins, John Monro
1Wessex Cardiothoracic Centre, Southampton University Hospital, Southampton, United Kingdom. akramasaleh@yahoo.com
Insights
Heart failure is the primary surgical indication for infective endocarditis. Valve replacement surgery, particularly with mechanical prostheses, is safe and effective, showing low mortality rates.
Area of Science:
- Cardiology
- Cardiac Surgery
- Infectious Diseases
Background:
- Infective endocarditis (IE) is a serious infection affecting heart valves.
- Determining optimal surgical indications for IE is crucial for patient outcomes.
- Previous studies highlight varied surgical approaches and outcomes.
Purpose of the Study:
- To identify the primary surgical indications for treating infective endocarditis.
- To evaluate the early results and safety of surgical interventions for IE.
Main Methods:
- Retrospective analysis of 123 patients undergoing surgical treatment for IE between 1984-1994.
- Data collected included patient demographics, microbiology, risk factors, surgical indications, and outcomes.
- Focus on native and prosthetic valve endocarditis.
Main Results:
- Heart failure (84%) was the leading surgical indication for IE.
- Streptococcus and Staphylococcus were the most common pathogens.
- Hospital mortality was low at 1.6%, with few complications like heart block (4%) and stroke (2.4%).
Conclusions:
- Heart failure is the predominant indication for surgical intervention in infective endocarditis.
- Valve replacement using mechanical prostheses offers a safe and low-mortality treatment option for IE.
Objective:
The objective of this study is to determine the surgical indication in the treatment of infective endocarditis.
Setting:
Retrospective study in a tertiary care--Wessex Cardiothoracic--Centre.
Subjects And Design:
Case records of patients admitted with infective endocarditis for surgical treatment between 1984 to 1994 at Wessex Cardiothoracic Centre were analysed. This analysis includes the age, sex, microbiology results, risk factors, surgical indication and early results.
Results:
A total of 123 patients was admitted with bacterial endocarditis treated surgically since 1984. The mean age was 51.9 years with male:female ratio of 3:1. The most common causative organism was streptococcus (63%) and staphylococcus (30%). Native valve endocarditis occurred in 111 patients, affecting the aortic, mitral, combined aortic and mitral valve in 69%, 33%, and 8% of cases, respectively. Late prosthetic valve endocarditis occurred in 12 patients. The most common indication for surgery was heart failure (84%), uncontrolled sepsis (8%), and recurrent endocarditis (2.5%). Hospital mortality was 1.6%. Complete heart block and cerebrovascular accident developed in 4% and 2.4%, respectively.
Conclusions:
Heart failure is the main indication for surgery. Valve replacement with mechanical prosthesis is a safe procedure with a low rate of mortality and complication.
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