Related Experiment Videos
[RNA-based transgene silencing: mechanism and applications]
Wen Chen1, Dong Wang, Yi-Kun He
1Biology Department, Capital Normal Universit, Beijing 100037, China.
Yi Chuan = Hereditas
|January 11, 2005
Abstract:
RNA-based transgene silencing is a phenomenon that endogenous and exogenous mRNAs are degraded specifically directed by double-stranded RNA. Here we review the recent advances on its mechanism and summarize related proteins and expatiate their functions. Furthermore,we introduce the enormous potential of dsRNA as a tool in functional genomics research and practical biotechnology.