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Exercise and insulin-mediated capillary recruitment in muscle
Stephen Rattigan1, Catherine Wheatley, Stephen M Richards
1Department of Biochemistry, Medical School, University of Tasmania, Private Bag 58, Hobart, Tasmania, 7001, Australia. S.Rattigan@utas.edu.au
Exercise and Sport Sciences Reviews
|January 11, 2005
Abstract:
Blood flow to contracting muscles is increased rapidly and is redistributed within the muscle. Recent research has highlighted that insulin causes similar changes, but these are absent in insulin resistance, resulting in impaired insulin-mediated muscle glucose uptake. Understanding the mechanisms and interactions between contraction- and insulin-mediated alterations in blood flow within muscle may reveal new approaches to overcome insulin resistance.