Related Experiment Video
Updated: Aug 20, 2026

An Advanced Murine Model for Nonalcoholic Steatohepatitis in Association with Type 2 Diabetes
Published on: April 26, 2019
[Obesity and its association with cryptogenic cirrhosis and hepatocarcinoma]
Javier Lizardi-Cervera1, Daniel Motola-Kuba, Luis Guevara-González
1Clínica de Gastroenterología y Unidad de Hígado, Fundación Clínica Médica Sur, México DF. jilizardi@medicasur.org.mx
Abstract:
Obesity is a rapidly growing health issue in Mexico and throughout the world because it is perceived as an alarming threat directly related with lifestyle in both children and adults, although cardiovascular, metabolic, neoplasic, and sleep-disorder complications of obesity are being investigated. However, overweight is a risk factor for chronic liver disease because liver fibrosis can develop in overweight patients free of any other known causes of liver disease. Obesity has been associated with development of hepatocellular carcinoma.
Related Concept Videos
Cirrhosis I: Introduction
Cirrhosis II: Pathophysiology
Obesity
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Cholecystitis

