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High-resolution reference ranges for estradiol, luteinizing hormone, and follicle-stimulating hormone in men and
Anand S Dighe1, Joseph M Moy, Frances J Hayes
1Clinical Chemistry Laboratory, Department of Pathology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA. asdighe@partners.or
Objectives:
High-resolution reference ranges are essential for reproductive hormones due to the significant day-to-day variation seen with these analytes.
Design And Methods:
The performance of AxSYM assays for estradiol, luteinizing hormone (LH), and follicle-stimulating hormone was evaluated.
Results:
These studies validate the performance of each assay, permitting high-resolution reference ranges to be established.
Conclusions:
The high-resolution reference range data provided herein for both normally cycling females and males should be applicable to a wide variety of clinical situations.
