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Updated: Aug 20, 2026

05:14
Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
Published on: September 8, 2021
Magnetic resonance relaxometry in monozygotic twins discordant and concordant for schizophrenia
Filip Spaniel1, Vit Herynek, Tomas Hajek
1Psychiatric Center Prague, Ustavni 91, 181 03 Prague 8, Bohnice, Czech Republic. spaniel@pcp.lf3.cuni.cz
Abstract:
T1 and T2 relaxation times were examined in four pairs of monozygotic (MZ) twins discordant and concordant for schizophrenia with low and high genetic loading for the illness and five healthy control MZ twin pairs. Patients with schizophrenia (n = 11) showed significant prolongation in T1 relaxation times in the globus pallidus (GP) bilaterally (P < 0.005, Bonferroni corrected) when compared to 14 healthy MZ twins.
