Related Experiment Video
Updated: Aug 20, 2026

Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
Published on: November 17, 2014
[Corneal transplantation--immunological mechanisms of rejection episode]
Lukasz Cwalina1, Ewa Mrukwa-Kominek
1Z Katedry i Kliniki Okulistyki Slaskiej Akademii Medycznej w Katowicach.
Abstract:
Organ transplantation including cornea is often only the one method of treatment in case of their irreversible destruction. The genetic difference between donor and graft recipient makes the immunological system recognizes foreign antigens and triggers off a rejection episode. This article reviews corneal graft rejection immunology and indicates possible future options for the clinical evaluation of more specific therapeutic agents that modulate the immunological mechanisms of allograft rejection. It discusses also the role of HLA matching in the survival of corneal grafts especially in "high risk" eyes.
Related Concept Videos
Cell-mediated Immune Responses
Kidney Transplant II: Surgical Procedure
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant III: Nursing Management
Kidney Transplant I: Introduction
