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Updated: Aug 20, 2026

A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
Published on: October 24, 2015
[Cutaneous and bone metastases revealing hepatocarcinoma]
Juliette Jegou1, Philippe Perruzi, Eric Arav
1Service de Médecine Interne et des Maladies Infectieuses, Hôpital Robert Debré. jjegou@chu-reims.fr
Abstract:
We report the case of a 55-year-old patient who was admitted to our hospital for a frontal tumor. He had a left forehead nodule that had appeared several weeks before, measuring 6 cm in diameter. On palpation, it was painless and there was a pulse, and the skin above was non ulcerated. Radiography and computed tomographic scan of the skull suggested a subcutaneous metastasis. Computed tomographic scans of the lung and the abdomen showed a heterogeneous liver with irregular outlines and secondary adrenal infiltrations. A biopsy of the frontal tumor confirmed a metastatic hepatocellular carcinoma.
