Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Ultrastructural renal damage after shock wave exposure].

T Saitoh1, S Orikasa, N Ioritani

  • 1Department of Urology, Tohoku University School of Medicine.

Nihon Hinyokika Gakkai Zasshi. the Japanese Journal of Urology
|January 1, 1992
PubMed
Summary

Underwater shock waves cause direct kidney damage, particularly to proximal tubules. Electron microscopy revealed cellular destruction and organelle damage in rabbit kidneys after exposure.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biochemical and ultrastructural analyses of IgLON cell adhesion molecules, Kilon and OBCAM in the rat brain.

Neuroscience·2003
Same author

[Surgical treatment for pulmonary metastases from colorectal cancer].

Kyobu geka. The Japanese journal of thoracic surgery·2003
Same author

Toxicity assessment of 255 chemicals to pure cultured nitrifying bacteria using biosensor.

Water science and technology : a journal of the International Association on Water Pollution Research·2003
Same author

Sarcomatoid transitional cell carcinoma originating from a duplicated renal pelvis.

International journal of urology : official journal of the Japanese Urological Association·2002
Same author

Metastasis of renal cell carcinoma to central nervous system hemangioblastoma in two patients with von Hippel-Lindau disease.

Pathology international·2002
Same author

Spontaneous regression of hepatocellular carcinoma--a case report.

Hepato-gastroenterology·2002

Area of Science:

  • Renal pathology
  • Cellular ultrastructure
  • Shock wave effects

Context:

  • Investigating the impact of high-intensity underwater shock waves on renal tissue.
  • Utilizing piezo-ceramics to generate shock waves (1200 bar) for experimental exposure.
  • Examining rabbit renal cortex ultrastructure via electron microscopy.

Purpose:

  • To elucidate the direct ultrastructural damage to renal cells induced by shock wave exposure.
  • To characterize the progression and nature of renal cell injury following varying levels of shock wave exposure.
  • To differentiate shock wave-induced renal injury from other forms of renal insult, such as ischemia.

Summary:

  • Shock wave exposure (1200 bar) caused significant renal ultrastructural damage, primarily in proximal tubules.

Related Experiment Videos

  • Observed damage included vacuole formation, brush border loss, organelle destruction, and cellular desquamation.
  • Progressive damage affected distal tubules and led to tubular atrophy and scarring one week post-exposure.

    • Impact:

    • Demonstrates direct cellular damage to the kidney from underwater shock waves.
    • Provides critical ultrastructural evidence of shock wave-induced renal injury.
    • Highlights the distinct pathology of shock wave damage compared to ischemic injury.