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Related Experiment Videos

Pelvic exenteration in the elderly patient.

C M Matthews1, M Morris, T W Burke

  • 1Department of Gynecology, University of Texas M.D. Anderson Cancer Center, Houston.

Obstetrics and Gynecology
|May 1, 1992
PubMed
Summary

Radical exenterative surgery in older patients (age 65+) shows comparable survival and mortality rates to younger patients. While complications are common, many are infectious and not life-threatening, suggesting age alone isn't a contraindication.

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Geriatric Surgery

Background:

  • Advanced age is often considered a contraindication for radical exenterative surgery.
  • Pelvic exenteration is a complex procedure with significant morbidity.

Purpose of the Study:

  • To evaluate the outcomes of pelvic exenteration in elderly patients (age 65 and older).
  • To compare the outcomes of pelvic exenteration in elderly patients versus younger patients.

Main Methods:

  • Retrospective review of 63 patients aged 65+ who underwent pelvic exenteration (1960-1991).
  • Analysis of complication rates, operative mortality, recurrence, and survival.
  • Comparison with 363 younger patients undergoing the same procedure.

Main Results:

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  • 38% experienced major complications, 38% minor; 60% had infectious complications.
  • Operative mortality was 11% in the older group vs. 8.5% in the younger group (not significant).
  • 5-year survival was 46% in the older group vs. 45% in the younger group (not significant).

Conclusions:

  • Pelvic exenteration can be performed in elderly patients with outcomes comparable to younger patients.
  • Infectious morbidity is common but often manageable.
  • Age alone should not be a contraindication for radical exenterative surgery.