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Chromobacterium violaceum septicaemia from north India

Pallab Ray1, Jyoti Sharma, Rungmei S K Marak

  • 1Department of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh 160012, India. pallab@sancharnet.in

The Indian Journal of Medical Research
|January 18, 2005
PubMed

Insights

Chromobacterium violaceum infections are rare but deadly. This report details a rare case of C. violaceum septicemia in a child from North India, successfully treated with antibiotics.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases

Background:

  • Chromobacterium violaceum is a Gram-negative bacterium found in tropical and subtropical soil and water.
  • Human infections are infrequent but associated with high mortality rates.
  • Previous reports from India are limited to the southern and eastern regions.

Observation:

  • A 6-year-old boy from North India presented with high fever, anemia, neutrophilic leukocytosis, and bilateral chest infiltrates.
  • C. violaceum was isolated from blood and pus cultures.
  • The patient exhibited symptoms consistent with severe sepsis.

Findings:

  • This case represents the first documented instance of C. violaceum septicemia in North India.
  • The patient demonstrated a successful clinical outcome following treatment with ciprofloxacin and amikacin.
  • This is the only reported Indian case of C. violaceum septicemia with survival.

Implications:

  • Highlights the potential for C. violaceum to cause severe infections in previously unreported geographical areas.
  • Emphasizes the importance of considering C. violaceum in the differential diagnosis of sepsis, especially in febrile patients with relevant exposure history.
  • Demonstrates the efficacy of fluoroquinolones and aminoglycosides in treating C. violaceum infections.

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