B-raf and a B-raf pseudogene are located on 7q in man
G Sithanandam1, T Druck, L A Cannizzaro
1Biological Carcinogenesis and Development Program, PRI/Dyncorp, Frederick Cancer Research and Development Center, Maryland 21702-1201.
Oncogene
|April 1, 1992
Abstract:
The B-raf gene was localized to human chromosome region 7p11-7qter by Southern blot analysis of its segregation in a panel of rodent-human hybrids, using a B-raf cDNA clone. Chromosomal in situ hybridization refined the localization to 7q33-36. Analysis of genomic B-raf clones identified a B-raf pseudogene in addition to the active gene. Based on the chromosomal mapping data we conclude that the pseudogene is located near the active gene.
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