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[Studies on HPLC fingerprints of tanshinone microemulsion]
Hui-yi Lv1, Qing Fan, Ning Zhang
1Department of Pharmacy, Second Affiliated Hospital of Dalian Medical University, Dalian 116027, China.
Objective:
To establish the HPLC fingerprints of tanshinone microemulsion.
Method:
HPLC analysis was carried on Hypersil C18(4.6 mm x 250 mm, 5 microm) analytical column; the acetonitrile and 0.5% phosphoric acid solution were used as mobile phases with gradient elution at a flow rate of 1.0 mL x min(-1). The UV detection wavelength was set at 270 nm.
Result:
Six peaks on HPLC fingerprint of Tanshinone Microemulsion are indexed.
Conclusion:
The method developed in the present study is convenient, reliable, and can be used as a quality control method for Tanshinone Microemulsion.
