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Updated: Jan 14, 2026

In Vivo CRISPR/Cas9 Screening to Simultaneously Evaluate Gene Function in Mouse Skin and Oral Cavity
Published on: November 2, 2020
Nature and nurture - lessons from chemical carcinogenesis
1Massachusetts Institute of Technology, Center for Cancer Research, 77 Massachusetts Avenue, E17-132, Cambridge, Massachusetts 02319, USA. luch@mit.edu
Abstract:
The roles of genetic constitution versus environmental factors in cancer development have been a matter of debate even long before the discovery of 'oncogenes'. Evidence from epidemiological, occupational and migration studies has consistently pointed to environmental factors as the major contributing factors to cancer, so it seems reasonable to discuss the importance of chemical carcinogenesis in the present 'age of cancer genetics'.
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