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[Rheumatic fever. Its current status based on 4 cases].

N Satz1, A Hany, U Meister

  • 1Medizinische Klinik und Rheumaklinik, Kantonsspital Winterthur.

Schweizerische Medizinische Wochenschrift
|April 11, 1992
PubMed
Summary

Rheumatic fever can occur after mild sore throats, presenting diagnostic challenges. Prompt treatment and continuous prophylaxis are crucial to prevent recurrences of this inflammatory condition.

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[Not Available].

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Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Pediatrics

Background:

  • Rheumatic fever is an inflammatory condition that can affect the heart, joints, brain, and skin.
  • It is a sequel to infection with group A Streptococcus.

Observation:

  • Four patients with rheumatic fever were hospitalized over a 12-month period.
  • All patients had a preceding non-severe sore throat.
  • Polyarthritis was the predominant major symptom in three cases; monarthritis in one.

Findings:

  • Diagnosis was based on the revised Jones criteria in most cases.
  • Minor symptoms included fever, arthralgia, elevated C-reactive protein (CRP), and antistreptolysin O.
  • Joint symptoms resolved with nonsteroidal anti-inflammatory drugs.
  • One patient experienced a recurrence despite adequate secondary prophylaxis with benzathine penicillin.

Implications:

  • The study highlights diagnostic difficulties due to evolving clinical presentations of rheumatic fever.
  • Emphasizes the importance of treating streptococcal sore throat to prevent initial rheumatic fever episodes.
  • Underscores the necessity of continuous secondary prophylaxis to prevent recurrent rheumatic fever.

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