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Published on: June 8, 2021
The effectiveness of risperidone in the treatment of three children with feeding disorders
Paul Berger-Gross1, Daniel J Coletti, Karen Hirschkorn
1Department of Medical Services, St. Mary's Healthcare System for Children, Bayside, New York 11360, USA. pbergwrgross@stmaryskids.org
Insights
Risperidone may help children with severe feeding disorders and anxiety. This medication aided oral intake and weight gain when behavioral therapy was insufficient.
Area of Science:
- Pediatric Rehabilitation
- Child Psychiatry
- Clinical Nutrition
Background:
- Children with extensive early childhood medical histories, particularly gastrointestinal interventions, often experience persistent feeding problems.
- Failure-to-thrive (FTT) and comorbid anxiety/mood symptoms complicate severe feeding disorders in these children.
- Traditional behavioral feeding therapies may be insufficient for complex cases.
Observation:
- A case series involving 3 preadolescent children (ages 7-9) with severe feeding disorders, FTT, and psychiatric comorbidities was conducted.
- These children received inpatient multidisciplinary treatment including behavioral and psychopharmacologic interventions.
- Risperidone was added to the treatment regimen for all three patients.
Findings:
- The addition of risperidone led to significant increases in oral intake and accelerated weight gain across the patient group.
- Two out of three children were able to discontinue assistive feeding interventions.
- One patient experienced a 74% reduction in enteral nutritional support.
Implications:
- Risperidone shows potential as a safe and effective adjunctive treatment for pediatric feeding disorders with complex medical and psychiatric profiles.
- This approach may be beneficial when standard behavioral feeding therapy yields limited success.
- Further research into risperidone's role in pediatric feeding rehabilitation is warranted.
Abstract:
Children with histories of extensive medical interventions in early childhood, especially those involving the gastrointestinal tract, are at-risk for residual feeding problems long after the medical issues have resolved. This case series describes the inpatient multidisciplinary treatment of 3 consecutive preadolescent children (ages 9, 8, and 7 years) admitted to our rehabilitation facility. Each child was admitted with a severe feeding disorder and histories of failure-to-thrive (FTT) that had required enteral nutritional interventions. Each child also had comorbid anxiety and mood symptoms. The addition of risperidone to behavioral and psychopharmacologic treatments was observed to significantly increase oral intake and accelerate weight gain. In 2 of 3 patients, assistive feeding interventions were successfully discontinued; and in a 3rd patient, enteral nutritional support was reduced by 74%. These cases suggest that risperidone may be a safe and effective adjunctive treatment, when behavioral feeding therapy is not sufficiently successful for children who have chronic and complicated medical and psychiatric presentations.
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