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Updated: Aug 20, 2026
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Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Published on: February 9, 2021
Microwave-assisted synthesis of novel thiazolocarbazoles and evaluation as potential anticancer agents. Part III
Alexandra Testard1, Laurent Picot, Ingrid Fruitier-Arnaudin
1Laboratoire de Biotechnologie et Chimie Bio-organique, FRE CNRS 2766, UFR Sciences Fondamentales et Sciences pour l'Ingénieur, Bâtiment Marie Curie, Université de la Rochelle, F-17042 La Rochelle cedex 1, France.
Journal of Enzyme Inhibition and Medicinal Chemistry
|January 25, 2005
Abstract:
Novel 6-substituted thiazolocarbazole derivatives have been synthesized under microwave irradiation via the corresponding imino-1,2,3-dithiazoles. In vitro antitumor potential of these polyheterocyclic compounds was evaluated. Among all the tested thiazolocarbazoles, compound 10 is the most effective in inhibiting cell growth.
