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Unusual combination of presenting features in multiple myeloma
T Baykul1, U Aydin, M K O Carroll
1Department of Oral and Maxillofacial Surgery, School of Dentistry, Suleyman Demirel University, Isparta, Turkey.
Dento Maxillo Facial Radiology
|January 25, 2005
Summary
Multiple myeloma can manifest with oral symptoms like numbness. Early detection through imaging and biopsy is crucial for diagnosing this plasma cell cancer.
Area of Science:
- Oral pathology
- Oncology
- Radiology
Background:
- Multiple myeloma is a plasma cell malignancy.
- Oral manifestations can be initial signs, including pain, swelling, and bone lesions.
Observation:
- A 62-year-old female presented with mandibular numbness.
- Radiographs showed osteolytic lesions and cortical destruction.
- Biopsy confirmed plasma cell myeloma.
Findings:
- Numbness indicated nerve involvement due to bone destruction.
- Imaging revealed diffuse osteolytic alterations in the mandible.
- Histopathology confirmed multiple myeloma.
Implications:
- Nerve dysfunction in the jaw can signal malignancy.
- Early oral examination is vital for multiple myeloma diagnosis.
- Radiographic and histopathological evaluations are key.