Effects of extracts from medicinal plants on the development of metastatic process

Area of Science:

• Oncology
• Pharmacognosy
• Immunology

Background:

• Metastasis remains a significant challenge in cancer treatment.
• Developing novel therapeutic strategies to prevent cancer spread is crucial.
• Traditional medicine often utilizes plant-derived compounds for therapeutic purposes.

Purpose of the Study:

• To investigate the potential of Siberian and Far Eastern plant preparations in inhibiting post-operative metastasis.
• To evaluate the impact of these plant preparations on the host's antitumor immunity.

Main Methods:

• Animal models with transplanted tumors were used.
• Tumor node removal was performed, followed by administration of plant preparations.
• Inhibition of metastases and stimulation of antitumor resistance were assessed.

Main Results:

• Plant preparations demonstrated the ability to inhibit metastases after tumor removal in experimental animals.
• The tested plant preparations effectively stimulated the organism's antitumor resistance.

Conclusions:

• Preparations derived from plants native to Siberia and the Far East show promise in preventing cancer metastasis.
• These findings suggest a potential role for phytotherapy in enhancing the body's immune response against cancer recurrence.