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Updated: Aug 19, 2026

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
Resistance of native and circulating modified low-density lipoproteins in human blood to association
I V Suprun1, A A Mel'nichenko, I A Sobenin
1Laboratory for Mechanisms of Atherogenesis, Institute of Experimental Cardiology, Russian Cardiology Research-and-Production Complex, Russian Ministry of Health. inat@cardio.ru
Abstract:
The resistance of native and circulating modified low-density lipoproteins from human blood to spontaneous and polyethylene glycol-induced association was studied by recording light transmission fluctuations. Circulating modified low-density lipoproteins were less resistant to association than native low-density lipoproteins. Polyethylene glycol-induced association of low-density lipoproteins was irreversible. Our results suggest that atherogenic activity of circulating modified low-density lipoproteins is associated with their increased predisposition to irreversible association.
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