The vital link between chronic disease and depressive disorders
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Published on: December 2, 2015
Daniel P Chapman1, Geraldine S Perry, Tara W Strine
1Emerging Investigations and Analytic Methods Branch, Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA. dpc2@cdc.gov
Insights
Depressive disorders are linked to a higher prevalence of chronic diseases, impacting both conditions. Understanding this relationship is vital for public health and healthcare, necessitating integrated treatment approaches.
Area of Science:
- Public Health
- Psychiatry
- Internal Medicine
Background:
- Chronic diseases represent a growing public health concern.
- Depressive disorders are increasingly prevalent and have a chronic course.
- Understanding the link between depression and chronic disease is crucial for healthcare.
Purpose of the Study:
- To review the association between depressive disorders and chronic diseases.
- To explore the bidirectional relationship between mental health and chronic conditions.
Main Methods:
- Medline search using keywords for mental disorders/depression and chronic diseases (asthma, arthritis, cardiovascular disease, cancer, diabetes, obesity).
Main Results:
- Depressive disorders are associated with an increased prevalence of chronic diseases.
- Depression can precipitate chronic diseases, and chronic diseases can worsen depression symptoms.
- The interplay between depression and chronic disease affects disease management and treatment.
Conclusions:
- Depressive disorders play a significant role in the development, progression, and outcomes of chronic diseases.
- Community-based research and interventions for detecting and treating depression are needed.
- Further research should investigate the role of other mental illnesses in chronic disease pathogenesis.
Introduction:
Chronic diseases have assumed an increasingly important role in public health research and intervention. Without treatment, depressive disorders characteristically assume a chronic course and are expected, by 2020, to be second only to heart disease in the global burden of disease. Thus, understanding the relationship between depressive disorders and chronic disease appears vital to public health assessment and health care delivery.
Methods:
Articles for review were primarily identified by a Medline search emphasizing the subject headings mental disorders or depression crossed with selected chronic diseases and conditions including asthma, arthritis, cardiovascular disease, cancer, diabetes, and obesity.
Results:
Mental illnesses - most specifically, depressive disorders - were associated with increased prevalence of chronic diseases. This association between depression and chronic disease appears attributable to depressive disorders precipitating chronic disease and to chronic disease exacerbating symptoms of depression. The complex interrelationship between depressive disorders and chronic disease has important implications for both chronic disease management and the treatment of depression.
Conclusion:
Depressive disorders assume an important role in the etiology, course, and outcomes associated with chronic disease. Multivariate community-based research and intervention fostering the detection and treatment of depressive disorders is needed, as is further examination of the role exerted by mental illnesses other than depression in the pathogenesis of chronic disease.
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