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The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
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The vulva encompasses the external structures of the female reproductive system. At the forefront is the monpubis, a cushion of fatty tissue atop the pubic bone. Once puberty sets in, this area typically grows hair. Extending from just behind the mons pubis are the labia majora (labia = 'lips'; majora = 'larger'), which are larger skin fs olds coated with hair. Nestled within are the labia minora (labia = 'lips'; minora = 'smaller'), which are thinner, more...
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Updated: Apr 3, 2026

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
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[Vaginal ecosystem].

I Karag'ozov, E Shopova, P Andreeva

    Akusherstvo I Ginekologiia
    |January 28, 2005
    PubMed
    Summary

    The vaginal ecosystem, though dynamic, is prone to disbiosys. Polygynax effectively restores ecological balance in bacterial vulvovaginitis caused by intestinal pathogens.

    Area of Science:

    • Medical ecology
    • Microbiology
    • Immunology

    Context:

    • The vagina maintains a unique, dynamic, yet unstable ecosystem.
    • Disruption of this equilibrium, known as disbiosys, involves various components like morphology, fluid, flora, acidity, and immune responses.

    Purpose:

    • To discuss the components of the vaginal ecosystem and its equilibrium.
    • To present clinical experience with Polygynax for treating bacterial vulvovaginitis.

    Summary:

    • The vaginal ecosystem comprises morphological, fluid, microbial, and immunological factors.
    • Bacterial vulvovaginitis, often caused by intestinal pathogens, disrupts this delicate balance.
    • Polygynax demonstrated efficacy in rapidly restoring the vaginal ecological equilibrium.

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    Impact:

    • Highlights the importance of vaginal ecological balance.
    • Suggests Polygynax as a rapid therapeutic option for bacterial vulvovaginitis.
    • Contributes to understanding microbial interactions in the vaginal environment.