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Updated: Jul 30, 2026

Comparative Lesions Analysis Through a Targeted Sequencing Approach
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Published on: November 5, 2019

Centromeric chromosomal translocations show tissue-specific differences between squamous cell carcinomas and

Mario Hermsen1, Antoine Snijders, Marta Alonso Guervós

  • 1Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands. mhermsen@hca.es

Oncogene
|January 28, 2005
PubMed
Summary

Structural chromosomal aberrations, specifically whole arm translocations, are more frequent in squamous cell carcinomas than adenocarcinomas. Different centromeric instability mechanisms contribute to these chromosomal changes in epithelial tumors.

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