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Related Experiment Videos

LINAC radiosurgery in skull base meningiomas.

R Deinsberger1, J Tidstrand, H Sabitzer

  • 1Department of Neurosurgery, Klagenfurt General Hospital, Klagenfurt, Austria. r.deinsberger@kh-st-poelten.at

Minimally Invasive Neurosurgery : MIN
|January 28, 2005
PubMed
Summary

LINAC radiosurgery effectively treats benign skull base meningiomas, achieving a 97.2% tumor control rate with minimal side effects. This approach enables less invasive treatment strategies, improving patient quality of life.

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Linac radiosurgery as a tool in neurosurgery.

Neurosurgical review·2005

Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Oncology

Background:

  • Benign skull base meningiomas require effective treatment strategies.
  • LINAC radiosurgery has become increasingly accessible for these tumors.

Purpose of the Study:

  • To evaluate the efficacy and safety of LINAC radiosurgery for benign skull base meningiomas.
  • To assess the impact of LINAC radiosurgery on treatment strategies and patient outcomes.

Main Methods:

  • Retrospective analysis of 37 patients treated with LINAC radiosurgery between 1996 and 2003.
  • Treatment involved a combination of University of Florida and Radionics X Knife systems.
  • Doses ranged from 12.8 to 18 Gy, with a median volume of 5.9 mL.

Main Results:

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  • Tumor control rate of 97.2% observed over a median follow-up of 66 months.
  • Significant tumor size reduction in 32.4% of patients, decreased enhancement in 29.7%.
  • Low morbidity with only 5.6% experiencing transient neurological worsening.

Conclusions:

  • LINAC radiosurgery is an effective treatment for skull base meningiomas.
  • It facilitates a less aggressive surgical approach, improving quality of life.
  • Combining microsurgery and radiosurgery achieves high tumor control with acceptable morbidity.