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Related Experiment Videos

Linac radiosurgery as a tool in neurosurgery.

R Deinsberger1, J Tidstrand

  • 1Department of Neurosurgery, Klagenfurt General Hospital, Austria. r.deinsberger@kh-st-poelten.at

Neurosurgical Review
|February 24, 2005
PubMed
Summary

Linear accelerator (LINAC) radiosurgery effectively treats brain metastases and skull base meningiomas, offering high tumor control rates and improved patient quality of life.

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Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Medical Physics

Background:

  • Stereotactic radiosurgery precisely delivers high radiation doses to intracranial targets.
  • Linear accelerators (LINACs) have advanced to match gamma unit precision for radiosurgery.

Purpose of the Study:

  • To evaluate the efficacy of LINAC radiosurgery for various intracranial conditions.
  • To assess tumor control rates and survival outcomes in patients treated with LINAC radiosurgery.

Main Methods:

  • Treated 237 patients using LINAC radiosurgery between January 1996 and August 2003.
  • Utilized a combination of University of Florida and Radionics X Knife systems.
  • Treated brain metastases, skull base meningiomas, and other neurosurgical conditions.

Main Results:

  • Achieved an 89.4% local tumor control rate for 161 brain metastases.
  • Observed a 54.9% 1-year survival rate with a median survival of 54 weeks for brain metastases.
  • Attained a 97.2% 5-year local tumor control rate for 57 skull base meningiomas.

Conclusions:

  • LINAC radiosurgery is a valuable tool in neurosurgery, particularly for brain metastases and skull base meningiomas.
  • It facilitates less aggressive, multimodality treatment approaches.
  • Offers an alternative to open surgery and serves as an effective adjuvant therapy to enhance tumor control and minimize morbidity.

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