Transradial bilateral cardiac catheterization and endomyocardial bioposy: a feasibility study
Carey D Moyer1, Ian C Gilchrist
1Division of Cardiology, MS Hershey Medical Center, Pennsylvania State University, Hershey, Pennsylvania 17033, USA.
Insights
Transradial cardiac catheterization using forearm veins enables cardiac biopsy, offering an alternative to traditional femoral approaches. This technique is safe and effective for postcardiac transplant management.
Area of Science:
- Cardiology
- Vascular Surgery
- Interventional Cardiology
Background:
- Transradial cardiac catheterization is typically used for arterial procedures.
- The forearm venous approach for cardiac catheterization and biopsy is less explored.
- Endomyocardial biopsy is crucial for diagnosing transplant rejection and myocardial conditions.
Purpose of the Study:
- To describe a technique for transradial cardiac catheterization with concurrent cardiac biopsy.
- To evaluate the feasibility and safety of this transradial approach.
- To compare transradial and transfemoral approaches for cardiac biopsy in postcardiac transplant patients.
Main Methods:
- A retrospective case series of transradial cardiac catheterization with cardiac biopsy was conducted.
- Transfemoral procedures with biopsy by the same operator served as a comparison group.
- Standard transradial/femoral approaches were used, with a 7 Fr sheath inserted via forearm or femoral vein. Right heart catheterization and endomyocardial biopsy were performed.
Main Results:
- Eight transradial and twelve transfemoral procedures were performed for postcardiac transplant management.
- Procedure durations were similar: median 73 minutes (transradial) vs. 68 minutes (transfemoral).
- No procedural complications were reported in either group.
Conclusions:
- Bilateral cardiac catheterization with concurrent endomyocardial biopsy is technically feasible via a transradial/forearm venous approach.
- This transradial technique offers a safe and effective alternative for selected patients needing cardiac biopsy.
- The transradial approach presents advantages over the transfemoral route for specific cardiac procedures.
Abstract:
A case series and technique of transradial cardiac catheterization with cardiac biospy are described. Transradial cardiac catheterization is perceived to be limited to arterial procedures. Using the veins of the forearm, we have converted many previous femoral arterial/venous cardiac procedures to a transradial/forearm approach. Retrospective review of patients undergoing transradial procedures with concurrent cardiac biopsies was undertaken. A convenience sample of transfemoral procedures with biopsies performed by the same operator was identified for comparison. Coronary angiography/left heart catheterization was performed using standard transradial/femoral approaches. A 7 Fr introducer sheath was placed via a large median forearm or femoral vein. Right heart catheterization was done using a 120 cm balloon-tipped catheter and endomyocardial biopsy was performed with a 7 Fr biotome. Both groups were then compared for baseline characteristics and procedural events. Transradial (n = 8) and transfemoral (n = 12) procedures were all done for postcardiac transplantation management. There was no crossover between groups. Durations of the radial procedures (median, 73 min; range, 40-95) were similar to transfemoral procedures (median, 68 min; range, 45-105). No procedural complications were reported. Endomyocardial biopsy plays an important role in the diagnosis of transplant rejection and identification of pathological processes that cause myocardial dysfunction. Transradial cardiac catheterization has some clear advantages over a transfemoral approach. Bilateral cardiac catheterization with concurrent cardiac biopsy is technically feasible using a transradial/forearm approach. This approach offers an alternative approach for selected patients in need of cardiac biopsy.
Related Concept Videos
Cardiac Catheterization I: Pre-Procedure Overview
Cardiac Catheterization II: Right Heart Catheterization
Cardiac Catheterization III: Left Heart Catheterization

