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Updated: Jul 31, 2026

Chronic Constriction Injury of the Rat's Infraorbital Nerve (IoN-CCI) to Study Trigeminal Neuropathic Pain
Published on: September 21, 2015
Facial pain from visceral origin
Introduction:
Unilateral facial pain in the trigeminal area is known to be caused by a cancer in the superior lobe of the lung.
Case Report:
A 65 year old male, heavy smoker, presented a permanent otalgia and a mandibular pain on the left side. These symptoms could not be relieved by common analgesics. All explorations for common etiologies were negative. After an episode of dyspnea, a left lung cancer was discovered. Thanks to radiotherapy and chemotherapy, the patient's pain was improved.
Conclusion:
Referred facial pain is rare and can be explained by the invasion of the tenth nerve by an upper lobe lung tumor. In most cases, the patient presents a right otalgia and pain in the area of V3. The diagnosis can be delayed from 1 month to 4 years after the onset of the pain. Referred facial pain is improved by the treatment of the causal lung cancer.
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